Fib4 Blood Test Calculator. Quick and easy: The FIB-4 calculator is a simple blood test that

Quick and easy: The FIB-4 calculator is a simple blood test that can be performed in a doctor's office or laboratory, and the results are available within a short time. It will appear in the oval on the far right (highlighted in yellow). 67 High Risk > 2. Validation of FIB-4 and comparison with other simple noninvasive indices for predicting liver fibrosis and cirrhosis in hepatitis B virus-infected patients. Free online tool for medical professionals. This is a health tool designed to determine significant fibrosis and cirrhosis of the liver with the FIB 4 index in conditions such as NASH (non-alcoholic steatohepatitis) or HCV (hepatitis C virus). Although you can use the calculators This fibrosis 4 (FIB4) score calculator reveals whether there is significant liver fibrosis of different stages associated to cirrhosis using patient age, AST & ALT. This scoring system relies on routine blood tests and patient age, making it accessible and cost-effective. This non-invasive calculation helps estimate fibrosis risk and guides further diagnostic decisions. 25 and all other liver screen blood tests show no abnormalities that require Hepatology Referral Calculate your FIB-4 score using age, AST, ALT, and platelet count to estimate liver fibrosis risk with age-adjusted interpretation. Non-invasively identify hepatic fibrosis Legal Notices and Disclaimer © 2020 QxMD Software Inc. Mar 24, 2025 · FIB-4 Score Explained: The FIB-4 score is a simple, non-invasive test used to assess the degree of liver fibrosis in patients with chronic liver diseases such as non-alcoholic fatty liver disease (NAFLD) and hepatitis C. The CHA2DS2-VASc Score for for Atrial Fibrillation Stroke Risk calculates stroke risk for patients with atrial fibrillation, possibly better than the CHADS2 score. Non-Invasive Calculations to Predict Liver Damage APRI and FIB-4 Talk to your doctor about using non-invasive calculations such as AST to Platelet Ratio Index (APRI) and Fibrosis-4 index for Liver Fibrosis (FIB-4) to determine if there is evidence of liver disease. Share The Fibrosis-4 score helps to estimate the amount of scarring in the liver. The FIB-4 test should be done annually in patients on treatment with methotrexate. Treat metabolic risk factors and if there is ongoing risk suggest repeating test in 3 years. A new test, “Fibrosis-4” (LAB5191), is available in Connect Care and on the APL General Laboratory Requisition. Ann Intern Med. The FIB-4 calculator allows you to rule out or confirm a diagnosis of advanced liver fibrosis in a non-invasive way. If NAFLD is suspected: Blood tests should be arranged to exclude alternative causes of liver disease and possible metabolic complications. Special precautions & notes: Please request a FBC (EDTA plasma) and also send a serum tube for AST and ALT. . Patients were followed from FIB-4 score to a severe liver outcome, a composite of cirrhosis, liver transplantation, and hepatocellular carcinoma. 67 Important Disclaimer This calculator is for educational purposes only. The risk of advanced liver fibrosis should be assessed using a non-invasive scoring system, such as the NAFLD Fibrosis Score (NFS), Fibrosis (FIB)-4 score or the Enhanced Liver Fibrosis (ELF) test. 3 - 2. A quick, non-invasive tool for assessing liver health. Manual calculation will no longer be required when it is ordered. Commonly used methods to confirm fibrosis include: - : The FIB-4 index is a non-invasive tool that calculates a fibrosis score based on age, AST, ALT A new test, “Fibrosis-4” (LAB5191), is available in Connect Care and on the APL General Laboratory Requisition. It helps estimate if there is any scarring (fibrosis) in your liver. FIB-4 Calculator available at: https Dec 7, 2024 · 1. Fibrosis-4 (FIB-4) Calculator Share The Fibrosis-4 score helps to estimate the amount of scarring in the liver. They combine standard laboratory results with factors such as age to calculate a score that estimates the amount of scarring in the liver. Take charge of your health, start now! The FIB-4 Score calculator computes the Fibrosis-4 score to measure the amount of scarring in a liver based on the patient's age, AST and ALT levels, and platelet count. Take charge of your health, start now! The Fibrosis (FIB)-4 score which uses 3 blood tests and your age The NAFLD Fibrosis Score which uses 4 blood tests and information about your age, weight (BMI) and whether you have diabetes The Enhanced Liver Fibrosis (ELF) test which uses a combination of 3 blood tests. Assess liver health quickly using our Liver Fibrosis Score Calculator featuring FIB-4, APRI, and NFS scoring methods. It may be of less value in patients with early fibrosis, but this is not important as there is no specific treatment for this group of patients. , all rights reserved. The score calculator seen above can easily be pulled up on a computer or phone when in clinic. - Diabetes Care 2025 Jul; 48:1057 Recommend FIB-4 screening as first-line assessment for liver fibrosis in type 2 diabetes and prediabetes patients by: The FIB-4 panel is also offered as the FIB-4 Index Panel With Reflex to Enhanced Liver Fibrosis (ELF) Score (test code 12734), with reflex testing performed at an additional charge with an additional CPT code. The Fibrosis-4 (FIB-4) Index for Liver Fibrosis is a non-invasive scoring system based on several laboratory tests that help to estimate the amount of scarring in the liver. Jun 27, 2025 · Learn what a FIB-4 score means for your liver health. Unlike liver biopsies, which involve taking a tissue sample from your liver, the FIB-4 calculator uses routine blood test results to estimate fibrosis levels. Use The Enhanced Liver Fibrosis (ELF™) blood test is a simple, accurate, non-invasive test that provides a simple, unitless numeric score that is generated via an algorithm for use in advanced liver fibrosis. Apr 29, 2025 · Early detection helps guide treatment and prevent progression to cirrhosis or liver failure. In the context of the FIB-4 index, fibrosis is categorized into different stages based on the FIB-4 score value: - F0-F1: FIB-4 score < 1. Nov 17, 2022 · ELF score defines a three-marker fibrosis test (TIMP-1, PIIINP, HA) for assessing advanced fibrosis in NAFLD, guiding referrals and monitoring intervals. Any association between normally distributed continuous variable was tested using independent sample t-test, whereas Mann-Whitney U test was used for continuous data which is not normally distributed. The FIB-4 (Fibrosis-4) blood test is a simple, non-invasive way to check how healthy your liver is. Sample type: Plasma AND Serum Test name: FIB-4 a. Dive into our FIB-4 for Hepatic Fibrosis Calculator for a reliable assessment of liver health. The confirmation of fibrosis usually involves a combination of clinical evaluation, medical history, and various diagnostic tests. It uses readily available blood tests, including age, AST (aspartate aminotransferase), platelets, and ALT (alanine aminotransferase), to calculate the score. It is a simple calculation that uses routine blood tests to estimate the level of liver scarring or fibrosis. Result will be calculated if FIB-4 is requested, if not it can be calculated off line. Recommend referral to Metabolic Hepatology Clinic. Nov 18, 2020 · FIB-4 index helps rule out advanced liver fibrosis in NAFLD using age, AST, platelet count and ALT values with a <1. NASH FibroSure® Plus test is a noninvasive assessment of liver status in patients with nonalcoholic fatty liver disease (NAFLD). Dec 3, 2024 · Keywords: Liver fibrosis risk score, Fibrosis-4, Fibrosis-4 index Oct 3, 2024 · FIB-4 is widely used in assessing fibrosis in chronic hepatitis C and NAFLD but may not be applicable or validated for all types of liver diseases. The source for medical equations, algorithms, scores, and guidelines. Instructions Read the case history, use the FIB-4 calculator below to calculate the FIB-4 score, and then answer the Activity Question. 3 – 2. 45, the FIB-4 has a negative predictive value of 90% and sensitivity of 70% for ruling out advanced fibrosis. This test is particularly useful because it is derived from routine blood tests, making it accessible and cost-effective for monitoring liver health. FIB-4 Calculator available at: https The FIB-4 Score calculator computes the Fibrosis-4 score to measure the amount of scarring in a liver based on the patient's age, AST and ALT levels, and platelet count. Chou R, Wasson N. These non-invasive tests calculate scores based on blood test results, providing valuable information without the need for a liver biopsy, which is an invasive procedure. Liver blood tests — there may be a raised bilirubin, a high aspartate aminotransferase (AST) to alanine aminotransferase (ALT) ratio, and low albumin in advanced liver fibrosis. 2013;158:807-20. Jun 29, 2025 · Estimate liver fibrosis risk with the FIB-4 Calculator using age, AST, ALT, and platelet count. No part of this service may be reproduced in Dec 7, 2024 · 1. The FIB-4 score helps clinicians evaluate the need for FIB-4 Calculator Fibrosis-4 Index for Liver Fibrosis Assessment Fibrosis-4 index testing appears to be the best initial assessment for metabolic dysfunction–associated liver disease and should be used widely. A higher FIB-4 score indicates a greater likelihood of significant liver fibrosis, while a lower score suggests minimal or no fibrosis. Calculate FIB-4 score to assess liver fibrosis in patients with chronic liver disease and NAFLD. Non-invasive tools like the FIB-4 score provide a valuable way to estimate fibrosis severity without requiring a biopsy. If you have your platelet count, AST, and ALT values from a previous bloodwork, you can enter them yourself in the calculator here: Quick and easy: The FIB-4 calculator is a simple blood test that can be performed in a doctor's office or laboratory, and the results are available within a short time. 25 (Intermediate likelihood of significant fibrosis) - F3-F4: FIB-4 score > 3. Calculations […] Free online blood test calculators for medical professionals. Stage 4 - ELF test Request ‘NAFLD-ELF’ on ICE Samples will be referred to Biochemistry Laboratory at Leeds for analysis Samples will only be referred to Leeds for the ELF test if the FIB-4 is 1. Sequential measurement provides a pragmatic, tractable monitoring biomarker that refines risk assessment for liver events, cardiovascular events, and mortality. A higher FIB-4 score indicates a greater likelihood of advanced liver fibrosis. The score doesn’t say exactly how much scarring there is in your liver. al. 30 (No to minimal fibrosis) - F2: FIB-4 score 1. It is recognised that abnormal liver blood tests are an increasingly common presentation in primary care, in part due to the growing number of individuals with metabolic dysfunction associated steatotic liver disease (MASLD; formerly named non-alcoholic fatty liver disease [NAFLD]). 29, testing is reflexed to NASH FibroSure® Plus at an additional cost. This fibrosis 4 (FIB4) score calculator evaluates liver fibrosis based on age, platelet count, AST and ALT to help with cirrhosis diagnosis. Liver Fibrosis, Fibrosis-4 (FIB-4) Index Panel - The FIB-4 index is a simple non-invasive approach using selected laboratory measures (AST, ALT, platelet count) in combination with patient age to assess if an individual is at higher risk for advanced liver fibrosis (F3-F4). The AST to Platelet Ratio Index (APRI) determines the likelihood of hepatic fibrosis and cirrhosis in patients with Hepatitis C. This guideline does not apply to children. 5 High risk for advanced liver fibrosis. 67 (Indeterminate) ELF <9. 25 (Significant fibrosis or cirrhosis) Fibrosis stage 2 falls within the Feb 1, 2022 · This review evaluates the ability of the fibrosis index based on four factors (FIB-4) identifying fibrosis stages, long-time prognosis in chronic live… The ELF test is a non-invasive blood test which combines three direct serum biomarkers of liver fibrosis. Jun 18, 2025 · FIB-4 Index Calculator Estimate risk of advanced liver fibrosis in adults Patient Information Age (years) AST (U/L) ALT (U/L) Platelets (10⁹/L) Calculate FIB-4 Index Results – FIB-4 Index Score Interpretation Risk Categories Low Risk < 1. 45 rule-out threshold. Measures FIB-4 advanced fibrosis risk categorization (low, indeterminate, and high) was the primary predictor variable. The FIB-4 Index, a non-invasive and widely used clinical tool, is instrumental in the assessment of liver fibrosis, particularly in patients with chronic liver diseases … A higher FIB-4 score indicates a greater likelihood of significant liver fibrosis, while a lower score suggests minimal or no fibrosis. The Fib-4 index is a calculation. When the cutoff is set at <1. Oct 23, 2018 · The Fibrosis-4 (FIB-4) test is a calculator tool that also inputs routine laboratory values in addition to age to predict cirrhosis. Blood tests to diagnose fibrosis or cirrhosis in patients with chronic hepatitis C virus infection: a systematic review. Enter the required values to calculate the FIB-4 value. This calculator simplifies the calculation of the FIB-4 Index, making it an accessible tool for patients and healthcare providers to estimate liver fibrosis risk without invasive procedures. For additional testing options that include the FIB-4 index, consult the Quest online Test Directory. But what are the pitfalls of FIB-4? There are a few pitfalls of the FIB-4 score. What is the FIB-4 Score? The FIB-4 score is a non-invasive method used to assess liver fibrosis, particularly in patients with chronic liver diseases such as hepatitis C, hepatitis B, or non-alcoholic fatty liver disease (NAFLD). Although you can use the calculators The Fib-4 index is a calculation. As all of these tests are readily available to primary care physicians, FIB-4 is a highly accessible and affordable screening tool. This orderable will report FIB-4 score, each of AST, ALT and platelet test results, as well as interpretive comments based on FIB-4 value (Appendix 1). 25 (Significant fibrosis or cirrhosis) Fibrosis stage 2 falls within the Nov 16, 2025 · The FIB-4 (Fibrosis-4) index is a validated, non-invasive blood-based calculator that uses four readily available laboratory values—age, AST, ALT, and platelet count—to assess the risk of advanced liver fibrosis in patients with chronic liver disease, serving as the most recommended first-line screening tool to identify who needs further Liver fibrosis blood tests, such as FIB-4 and APRI, have shown good accuracy in identifying significant fibrosis and cirrhosis. "The ELF test* is a non-invasive blood test that measures three direct markers of fibrosis: hyaluronic acid (HA), procollagen III amino-terminal peptide (PIIINP), and tissue inhibitor of matrix metalloproteinase 1 (TIMP-1). Kim BK, et. This pathway employs blood tests to assess a patient’s risk of significant liver scarring, based on calculating their Fibrosis-4 score (FIB-4) using the following formula: The HAS-BLED Score for Major bleeding risk estimates risk of major bleeding for patients on anticoagulation to assess quality of atrial fibrillation care. Dec 18, 2023 · In addition to its value as a diagnostic tool, FIB-4 has clinical utility as a prognostic biomarker. FIB-4 and FIB-5 scores were calculated on the basis of the laboratory parameters. FIB-4 Calculator for NAFLD NB This is only valid for non-alcoholic fatty liver disease (NAFLD) and is intended for use in conjunction with the NCL Abnormal LFT pathway. 30-3. a. Liver fibrosis blood tests, such as FIB-4 and APRI, have shown good accuracy in identifying significant fibrosis and cirrhosis. Feb 3, 2025 · Apply for and manage the VA benefits and services you’ve earned as a Veteran, Servicemember, or family member—like health care, disability, education, and more. FIB-4 1. Enter age, AST, ALT, and platelets for an instant, accurate score. Ask for a copy of blood test results which are required for use with these calculators. Limitations: patients aged less than 35 years or over 65 years as the score is less reliable in these patients. 29, testing stops; if FIB-4 index value is greater than 1. FIB-4 index is calculated first; if FIB-4 index value is between 0 and 1. Fast, accurate, and free. To use ReachDeck to listen to or translate this site you must allow ReachDeck cookies For more information please visit our cookies page The FIB-4 score is calculated using the FIB-4 formula: FIB-4 = (Age * AST) / (Platelet count * √ALT) The FIB-4 score provides valuable information to healthcare professionals for assessing the degree of liver fibrosis and cirrhosis. Calculator: FIB-4 index, an indirect marker for liver fibrosis in adults (conventional units)* To continue reading this article, you must sign in with your personal, hospital, or group practice subscription. There are four criteria to be followed in the model as explained below: ■ Age– There is a correlation between age increase and the progression of fibr Jul 9, 2025 · Calculate the FIB-4 Index to non-invasively assess the risk of advanced liver fibrosis using age, AST, ALT, and platelet count. 3 Intermediate Risk 1. Fibrosis-4 index Condition / Indication: Screening index for NAFLD based on age, AST, ALT and platelet count. We would like to show you a description here but the site won’t allow us. Non-invasive methods are preferred whenever possible to avoid the need for invasive procedures like liver biopsies. Calculate various blood test ratios, indices, and scores. 5 Low risk for advanced liver fibrosis. It uses your age and the results of some of your blood tests to give an indication of the amount of scarring (fibrosis) in your liver. Calculate the Fibrosis-4 (FIB-4) Index to estimate liver fibrosis severity. ELF ≥9. These guidelines deal specifically with the management of abnormal liver blood tests in children and adults in both primary and secondary care under the following subheadings: (1) What constitutes an abnormal liver blood test? (2) What constitutes a standard liver blood test panel? (3) When should liver blood tests be checked? What are the FIB-4 score and Forns index tests? The FIB-4 score and Forns index are tests for diagnosing stages of liver fibrosis. Fibrosis-4 (FIB-4) Index for Liver Fibrosis – Noninvasive estimate of liver scarring to assess the need for biopsy (see MDcalc FIB-4 Score) Nonalcoholic fatty liver disease (NAFLD) is now the leading cause of chronic liver disease in the world. k. One of the great things about FIB-4 is that it is simple and the labs that are needed are readily available in most patients. Arrange blood tests to exclude co-existing liver disease (if there are abnormal liver blood test results) and metabolic conditions, depending on clinical judgement. Dec 30, 2024 · Calculation Example: The FIB-4 score is a non-invasive method used to assess the severity of liver fibrosis. Supports clinical decision-making and risk stratification. Use our FIB-4 Calculator to assess liver fibrosis risk quickly. 30 to 3. What Is the FIB-4 Calculator? The FIB-4 calculator is a medical tool used to assess the likelihood of liver fibrosis, which is the buildup of scar tissue in the liver.

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